Veillonellaceae
Bacteria › Bacillota › Negativicutes › Veillonellales › Veillonellaceae
MCA-BAC-000049
TaxID: 31977
| Rank: family
Biology & Ecology
Biology
Gram Statusgram-negative
Oxygen Toleranceobligate anaerobe
Morphologynot applicable
Key Traits
- short-chain fatty acid (SCFA) producer
Ecology
Primary Nichesgut, oral cavity
Reservoirhuman
Clinical Profile
Pathobiont
yes
no
context dependent
unknown
Clinical Rolesprotective commensal
Typical Specimenstool
Clinical Associations:
E1
E3 — Strong human clinical evidence
E2 — Moderate human evidence
E1 — Limited / preliminary
In a phase 1 FMT trial (n=10 anti-PD-1-refractory metastatic melanoma patients), Veillonellaceae relative abundance was higher in stool post-FMT plus nivolumab versus pretreatment (ANCOM); the responding FMT donor (Donor 1, whose recipients comprised all 3 clinical responders out of 5) was enriched for Veillonellaceae, and the paper explicitly characterizes the family as 'immunotherapy-favorable' based on prior anti-PD-1 cohort studies.
PMID:
33303685
D000069467
Fecal Microbiota Transplantation
D000069196
Gastrointestinal Microbiome
D000082082
Immune Checkpoint Inhibitors
D008545
Melanoma
H00038
Melanoma
Last reviewed: 2026-04-02
Evidence Timeline
Related Taxa
Shared Niche = same body site
Shared Risk = same vulnerable population
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