Bifidobacteriaceae
Bacteria › Actinomycetota › Actinomycetes › Bifidobacteriales › Bifidobacteriaceae
MCA-BAC-000005
TaxID: 31953
| Rank: family
Biology & Ecology
Biology
Gram Statusgram-positive
Oxygen Toleranceobligate anaerobe
Ecology
Primary Nichesgut
Reservoirhuman
Clinical Profile
Pathobiont
yes
no
context dependent
unknown
Clinical Rolesprotective commensal
Typical Specimenstool
Clinical Associations:
E2
E3 — Strong human clinical evidence
E2 — Moderate human evidence
E1 — Limited / preliminary
Bifidobacteriaceae relative abundance was depleted in critically ill ICU patients compared to healthy controls (ANCOM-II p-adj<0.1), representing a commensal family lost during critical illness-associated gut dysbiosis in a prospective cohort of 51 patients.
PMID:
36894652
E2
E3 — Strong human clinical evidence
E2 — Moderate human evidence
E1 — Limited / preliminary
Penalized ridge regression identified Bifidobacteriaceae as one of the most important families negatively associated with progressive Enterobacteriaceae enrichment between ICU days 1 and 3, consistent with a colonization resistance role against pathobiont expansion during critical illness.
PMID:
36894652
Last reviewed: 2026-04-01
Evidence Timeline
Related Taxa
Shared Niche = same body site
Shared Risk = same vulnerable population
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